Tag Archive for: Pimephales promelas

Fish short-term reproduction assay (OECD 229)

The fish short-term reproduction test is an in vivo screening assay that provides information about possible endocrine-mediated effects on adult fish. Within the OECD Conceptual framework for the testing and assessment of endocrine disrupting chemicals, it is a level 3 assay. We perform this test according to OECD test guideline 229 (Fish short-term reproduction assay, […]

New publication: Uptake and effects of the beta‐adrenergic agonist salbutamol in fish: supporting evidence for the fish plasma model

The fish plasma model predicts the fish blood plasma concentration of a pharmaceutical from the water concentration to which the fish is exposed and compares it to the human therapeutic plasma concentration with the postulate that no adverse toxic effects occur below this concentration. The present study provides several lines of evidence supporting the fish […]