The consideration of mixtures of chemical substances in the regulatory assessment of environmental risks is getting into the focus of competent authorities. Recent developments, particularly in the risk assessment of plant protection products and biocides, require nowadays the evaluation of mixture toxicity in the regulatory process.

Through research projects funded by environmental authorities, we have been involved in the development of concepts that include mixture toxicity considerations in the environmental risk assessment in a pragmatic, manageable and consistent way.

In various research projects, we have conducted experimental studies with mixtures and have applied mixture toxicity concepts to theoretically predict the effects of mixtures based on the effects of their individual components.

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