Tag Archive for: fathead minnow

Fish short-term reproduction assayK. Duis, M. Weil

Fish short-term reproduction assay (OECD 229)

The fish short-term reproduction test is an in vivo screening assay that provides information about possible endocrine-mediated effects on adult fish. Within the OECD Conceptual framework for the testing and assessment of endocrine disrupting chemicals, it is a level 3 assay. We perform this test according to OECD test guideline 229 (Fish short-term reproduction assay, […]

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fish early life stage testK. Duis, M. Weil

Fish early life stage test

Fish early-life stage tests are required for environmental risk assessments of industrial chemicals, plant protection products, biocides, and human and veterinary pharmaceuticals to evaluate chronic effects on the sensitive early life stages of fish. We perform these tests according to OECD test guideline 210 (Fish, early-life stage toxicity test, revised in 2013) in compliance with […]

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Technical proficiency study for OECD 229 with fathead minnowsK. Duis

Technical proficiency study for short-term reproduction assay

The fish short-term reproduction assay according to OECD test guideline 229 serves as Level 3 in vivo assay within the OECD Conceptual framework for the testing and assessment of endocrine disrupting chemicals. Laboratories aiming to conduct this assay must demonstrate their ability by performing a technical proficiency study with reference compounds. ECT has successfully completed […]

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Uptake and effects of the beta‐adrenergic agonist salbutamol in fish: supporting evidence for the fish plasma modelK. Duis

New publication: Uptake and effects of the beta‐adrenergic agonist salbutamol in fish: supporting evidence for the fish plasma model

The fish plasma model predicts the fish blood plasma concentration of a pharmaceutical from the water concentration to which the fish is exposed and compares it to the human therapeutic plasma concentration with the postulate that no adverse toxic effects occur below this concentration. The present study provides several lines of evidence supporting the fish […]

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