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Technical proficiency study for OECD 229 successfully completed – capacity for fish short-term reproduction assays available in 2021

The fish short-term reproduction assay according to OECD test guideline 229 serves as Level 3 in vivo assay within the OECD Conceptual framework for the testing and assessment of endocrine disrupting chemicals. Laboratories aiming to conduct this assay must demonstrate their ability by performing a technical proficiency study with reference compounds. ECT has successfully completed […]

New publication: Uptake and effects of the beta‐adrenergic agonist salbutamol in fish: supporting evidence for the fish plasma model

The fish plasma model predicts the fish blood plasma concentration of a pharmaceutical from the water concentration to which the fish is exposed and compares it to the human therapeutic plasma concentration with the postulate that no adverse toxic effects occur below this concentration. The present study provides several lines of evidence supporting the fish […]