After completion of a technical proficiency study in 2020 with three reference compounds (see news), ECT has successfully conducted a first fish short-term reproduction assay according to OECD test guideline 229 under GLP in 2021. We welcome inquiries for further OECD 229 studies using our in-house bred fathead minnows (Pimephales promelas) in 2022. For further […]
The fish short-term reproduction assay according to OECD test guideline 229 serves as Level 3 in vivo assay within the OECD Conceptual framework for the testing and assessment of endocrine disrupting chemicals. Laboratories aiming to conduct this assay must demonstrate their ability by performing a technical proficiency study with reference compounds. ECT has successfully completed […]
The SETAC North America 40th Annual Meeting takes place in Toronto (Canada) from 3 – 7 November 2019. ECT contributes with the following presentation:
The fish plasma model predicts the fish blood plasma concentration of a pharmaceutical from the water concentration to which the fish is exposed and compares it to the human therapeutic plasma concentration with the postulate that no adverse toxic effects occur below this concentration. The present study provides several lines of evidence supporting the fish […]
K. Duis
K. Duis
K. Duis