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New project started: ‘Prioritisation and risk evaluation of medicines in the environment’ (PREMIER)

The Innovative Medicines Initiative (IMI) project PREMIER aims to develop a centralised, user-friendly digital assessment system accessible for all relevant stakeholders. PREMIER will also explore options to incorporate environment considerations earlier in the drug development process to inform drug design and to reduce the need of animal testing. ECT is involved in this project as […]

Prioritisation and risk evaluation of medicines in the environment (PREMIER)

The Innovative Medicines Initiative (IMI) project ‘Prioritisation and risk evaluation of medicines in the environment’ (PREMIER) aims to develop a centralised, user-friendly and transparent digital assessment system accessible for all relevant stakeholders such as regulatory agencies, pharmaceutical industry, water managers and environmental non-governmental organisations. Furthermore, PREMIER will explore the options to incorporate environment considerations earlier […]

Review on the environmental fate and effects of water-soluble synthetic organic polymers

Because of their usually high molecular weight, polymers are generally considered as being of low environmental concern and are, therefore, exempted from registration and evaluation within REACH. This exemption is currently being reviewed by the European Commission. Against this background, data on the environmental fate and effects of selected water-soluble synthetic organic polymers used in […]

Review: Environmental risk assessment of pesticides in tropical terrestrial ecosystems

Despite the increasing use of pesticides in tropical countries, research and legislative efforts have focused on their temperate counterparts. In the present publication, the literature on environmental risk assessment of pesticides in tropical terrestrial ecosystems is reviewed. Potential differences in pesticide risks between temperate and tropical regions are evaluated, and research needs for tropical regions […]

New publication: Environmental risk or benefit? Comprehensive risk assessment of groundwater treated with nano Fe0-based Carbo-Iron®

For the treatment of groundwater contaminated with chlorinated hydrocarbons, nano-scaled zero-valent iron (nano Fe0) represents an efficient alternative to other treatments as e.g. pump & treat. Upon selection of a suitable treatment method for a given groundwater a risk-cost-benefit analysis is performed. This analysis does only rarely consider the potential risk of the remediation method […]

New publication: Compartment‐specific screening tools for persistence – potential role and application in the regulatory context

The persistence assessment under REACH relies on compartment‐specific degradation half‐lives derived from laboratory simulation studies with surface water, aquatic sediment or soil. Although these data are given priority, they are not available for most of the compounds. Therefore, according to the integrated assessment and testing strategy for persistence assessment, results from ready biodegradability tests are […]

Development and standardisation of an ecotoxicological test method using fungus gnat larvae for the risk assessment of genetically modified plants

Prior to releasing a genetically modified plant (GMP) into the environment and placing it on the market in the European Union, an environmental risk assessment has to be performed according to Directive 2001/18/EC. Based on the results of a previous project conducted from 2012 to 2016 (for more information, see the project description and the […]

New publication: Impact of an immunosuppressive human pharmaceutical on the interaction of a bacterial parasite and its invertebrate host

The interaction of pollutants and pathogens may result in altered (often enhanced) effects of the chemical, the biotic stressor or both. While standardised detection methods for immunotoxic effects of chemicals exist with regard to human health, such test systems are lacking for invertebrate species and no guidance is available on how immunotoxic effects of a […]