Tag Archive for: environmental risk assessment

New publication on TKTD modeling of sublethal endpoints for time‐variable toxicant exposure of CeriodaphniaK. Duis

New publication on TKTD modeling of sublethal endpoints for time‐variable toxicant exposure of Ceriodaphnia

Toxicokinetic-toxicodynamic (TKTD) modeling can integrate all available data from individual‐level bioassays into a single framework and enable refined risk assessments by extrapolating from laboratory results to time‐variable exposure scenarios. Dynamic energy budget (DEB) models coupled with TKTD modules (DEB-TKTD) are an approach to assess and predict sublethal effects of chemicals on individual organisms. However, thorough […]

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Fish short-term reproduction assayK. Duis, M. Weil

Fish short-term reproduction assay (OECD 229)

The fish short-term reproduction test is an in vivo screening assay that provides information about possible endocrine-mediated effects on adult fish. Within the OECD Conceptual framework for the testing and assessment of endocrine disrupting chemicals, it is a level 3 assay. We perform this test according to OECD test guideline 229 (Fish short-term reproduction assay, […]

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fish early life stage testK. Duis, M. Weil

Fish early life stage test

Fish early-life stage tests are required for environmental risk assessments of industrial chemicals, plant protection products, biocides, and human and veterinary pharmaceuticals to evaluate chronic effects on the sensitive early life stages of fish. We perform these tests according to OECD test guideline 210 (Fish, early-life stage toxicity test, revised in 2013) in compliance with […]

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Chemical sensitivity of earthworms from field populationsD. Leib

New publication on chemical sensitivity of earthworms from field populations

The environmental risk of pesticides for nontarget soil macroorganisms has mainly been assessed using the compost earthworm Eisenia fetida. However, E. fetida does not occur in agroecosystems and it is generally less sensitive than other earthworm species. Thus, the extrapolation of its response to pesticides to other earthworm species may lead to uncertainties in the […]

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Risk Assessment Innovation for Low-Risk Pesticides (RATION)

Risk Assessment Innovation for Low-Risk Pesticides (RATION)

Low-risk pesticides including biopesticides consisting of plant extracts, semiochemicals such as pheromones and allelochemicals, and microbial pesticides are gaining ground in the global market, where they have started to substitute synthetic pesticides. In addition, phages, protists, microbial consortia and double-stranded (ds)-RNA pesticides are emerging low-risk solutions that are expected to reach the market in coming […]

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New publication: Minimizing experimental testing on fish for legacy pharmaceuticals

Lead by Anja Coors, a team of partners in the IMI-funded project ‘Prioritisation and risk evaluation of medicines in the environment’ (PREMIER) developed and recently published a decision tree that shall help to minimize animal testing within PREMIER and beyond. The risk-driven decision tree uses a combination of experimental testing with non-vertebrates and a fish-specific […]

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Best chemical risk assessment professionals for maximum ecosystem services benefit (PRORISK)

PRORISK is a European Training Network funded by the European Union’s Horizon 2020 research and innovation programme. It creates a platform for training early-stage researchers in the field of advanced environmental risk assessment. Environmental risk assessment procedures are nowadays changing, incorporating for instance mechanistic, ecological, and socio-economic information. Consequently, risk assessments are becoming more comprehensive. […]

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Review of the environmental fate and effects of two UV filter substancesT. Junker

Review of the environmental fate and effects of two UV filter substances

Sunscreens containing UV filter substances, such as octocrylene (OCR) and butyl-methoxydibenzoylmethane (BMDBM), have been increasingly used to protect human skin against UV radiation. Both substances have been detected in monitoring studies in the freshwater and marine environment, and there has been concern about potential effects on aquatic organisms. In the present work, the environmental fate […]

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New project started: ARISTO

As acknowledged by the European Food Safety Authority (EFSA) soil microorganisms play a key role in ecosystem functioning and there is a lack of appropriate methods to assess impacts on them. ARISTO, the European Industry-Academia Network for Revising and Advancing the Assessment of the Soil Microbial Toxicity of Pesticides, started in 2021 and addresses this […]

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The European industry-academia network for revising and advancing the assessment of the soil microbial toxicity of pesticides (ARISTO)

The European Commission has imposed a stringent regulatory scheme for pesticide authorisation, which includes an assessment of potential risks for aquatic organisms and terrestrial macro-organisms. However, the assessment of the toxicity of pesticides on soil microorganisms relies on a protocol that does not identify effects on key microbial functions and on microbial diversity. As acknowledged […]

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