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Publication on validation of a method to determine transformation of chemicals in manure

Manure is widely used as a fertilizer and applied to agricultural land. It may contain highly active chemicals like veterinary medicinal products or biocides, which enter the environment by this pathway. This is recognized by several regulatory frameworks, however, a detailed method for examining the transformation of chemicals in manure was lacking. The present publication […]

Critical review and proposal for multigenerational testing in standard soil invertebrates

Standard laboratory tests to evaluate the effects of stressors (in most cases chemicals) on soil organisms offer a good compromise between feasibility and outcome, i.e. they should be reproducible and provide robust results. However, these tests may underestimate potential effects of prolonged exposures, particularly for persistent contaminants. In the last years, there was an increase […]

New test guideline: Anaerobic transformation of chemicals in liquid manure

New test guideline: Anaerobic transformation of chemicals in liquid manure

On 30 June 2022, the OECD published test guideline No. 320: ‘Determining anaerobic transformation of chemicals in liquid manure’. This guideline describes a standardised method to investigate transformation of chemical substances in pig and cattle liquid manure under anaerobic conditions. The experiments are performed to determine the rate of transformation of the test substance, the […]

Publication on enhanced ready biodegradability screening tests

In persistence assessment, enhanced ready biodegradability tests (eRBT) are used to close the gap between screening tests and complex simulation tests. However, only few data from such tests are available, and neither guidance on the design and interpretation of eRBTs, nor suitable validity criteria have been established so far. In a practical testing programme, five […]

New publication: Compartment‐specific screening tools for persistence – potential role and application in the regulatory context

The persistence assessment under REACH relies on compartment‐specific degradation half‐lives derived from laboratory simulation studies with surface water, aquatic sediment or soil. Although these data are given priority, they are not available for most of the compounds. Therefore, according to the integrated assessment and testing strategy for persistence assessment, results from ready biodegradability tests are […]

Report on assessment of environmental persistence

Report published on ‘Assessment of environmental persistence’

A literature study was performed to review the applicability of established and new tests for biodegradability for assessing persistence in the frame of PBT and vPvB assessments under REACH. Screening tests for ready and inherent biodegradability, proposals for enhanced ready tests as well as newly designed compartment-specific screening tests were analysed for strengths and weaknesses, […]