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Evaluation of a biotest battery for the ecotoxicological characterisation of waste: ring test with 60 laboratories from 15 countries

The ecotoxicological characterization of waste is part of its assessment as hazardous or non-hazardous according to the European List of Wastes (LoW, 2000/532/EC) amended by Directive 2008/98/EG and Regulation 2017/997. For this assessment, 15 hazard properties are evaluated. So far, there is no harmonised guidance for evaluation of the hazard property ‘ecotoxic’ (HP 14) using […]

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Supply of dung beetles for the performance of a ring test as a precondition for the implementation of an OECD Guidance Document

The objective of this project sponsored by the German Federal Environment Agency was the improvement of existing laboratory tests with dung beetles and dung flies. It was aimed at identifiying a second dung beetle species for standardised laboratory tests that should belong to the ecological group of ‘tunnelers’.  However, it was not possible to establish […]

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Development of a standardised laboratory test with dung beetles for the assessment of the ecotoxicity of veterinary pharmaceuticals

According to European law, the environmental risk assessment of veterinary pharmaceuticals for dung beetles is required for parasiticides for the treatment of pasture animals. Starting with recommendations from the SETAC advisory group DOTTS (Dung Organism Toxicity Test Standardisation), a test system using the widespread temperate dung beetle species Aphodius constans was developed. Together with the […]

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Organisation and performance of an international ringtest for the validation of the enchytraeid reproduction test

An enchytraeid reproduction test ring test was performed in line with OECD requirements. Twenty-nine institutions (mainly universities and contract research laboratories) from 15 countries from Europe and North America participated in this ring test. The co-ordinating laboratory centrally distributed the test chemicals, guidance papers and test organisms to all participants. In addition, several training courses […]

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Hardly soluble active ingredients of cosmetics – ecotoxicology and substitution

The aim of this project was to develop tools and to experimentally verify proposed assessment schemes such as the ‘poorly soluble approach‘ in order to enable a better assessment of highly lipophilic substances. In the context of a PhD project, selected highly lipophilic compounds present in personal care products (e.g. cosmetics) were investigated. ECT played […]

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Selection of test organisms for the environmental risk assessment of genetically modified plants: applying and testing a new selection procedure

Since almost two decades now, chemical stressors such as pesticides are subjected to a number of standardised ecotoxicity tests for regulatory approval prior to their release to the environment. Since the advent of the technology, genetically modified organisms (GMOs) in general, and genetically modified plants (GMPs) in particular have been a contentious issue  and, very […]

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C. Bandow

Development of a classification and assessment concept based on biodiversity of water and soil organisms regarding the effects of climate change and anthropogenic stressors

In July 2008, a new interdisciplinary research centre was founded in Frankfurt am Main (Germany) within the framework of the LOEWE Programme, a State Government of Hesse initiative for the development of scientific and economic excellence. The mission of the new centre (BiK-F) is to carry out internationally outstanding research on the interactions of organismic […]

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Assessing the long-term effects of the selected nanomaterial titanium dioxide – adaptation of testing procedures

Effects of the nanomaterial titanium dioxide NM-105 were studied in a sediment/water system with Lumbriculus variegatus according to OECD test guideline 225. Test media were prepared by mixing NM105 suspensions and the sediment-overlying water. Nominal test concentrations were confirmed by chemical analysis of Ti concentrations in the test media. Effects of titanium dioxide (NM-105) were […]

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Development of effective measures to reduce the environmental risk of human and veterinary pharmaceuticals

The environmental risks related to human and veterinary pharmaceuticals have to be assessed according to legal requirements within the authorisation procedures for pharmaceuticals. If a risk for the environment is indicated, risk mitigation measures should be proposed by the applicant and implemented within the risk management. The authorisation of a veterinary pharmaceutical can be refused […]

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