The aim of the project was the validation of a bioaccumulation test with terrestrial organisms (soil dwelling oligochaetes) by an international ring test. The test method was developed taking into account existing methods (UBA-reports 206 03 909 (1997) and 298 64 416 (2001)). A test protocol was prepared and used to run the test. A […]
The objective of this project sponsored by the German Federal Environment Agency was the improvement of existing laboratory tests with dung beetles and dung flies. It was aimed at identifiying a second dung beetle species for standardised laboratory tests that should belong to the ecological group of ‘tunnelers’. However, it was not possible to establish […]
According to European law, the environmental risk assessment of veterinary pharmaceuticals for dung beetles is required for parasiticides for the treatment of pasture animals. Starting with recommendations from the SETAC advisory group DOTTS (Dung Organism Toxicity Test Standardisation), a test system using the widespread temperate dung beetle species Aphodius constans was developed. Together with the […]
An enchytraeid reproduction test ring test was performed in line with OECD requirements. Twenty-nine institutions (mainly universities and contract research laboratories) from 15 countries from Europe and North America participated in this ring test. The co-ordinating laboratory centrally distributed the test chemicals, guidance papers and test organisms to all participants. In addition, several training courses […]
The aim of this project was to develop tools and to experimentally verify proposed assessment schemes such as the ‘poorly soluble approach‘ in order to enable a better assessment of highly lipophilic substances. In the context of a PhD project, selected highly lipophilic compounds present in personal care products (e.g. cosmetics) were investigated. ECT played […]
Since almost two decades now, chemical stressors such as pesticides are subjected to a number of standardised ecotoxicity tests for regulatory approval prior to their release to the environment. Since the advent of the technology, genetically modified organisms (GMOs) in general, and genetically modified plants (GMPs) in particular have been a contentious issue and, very […]
In July 2008, a new interdisciplinary research centre was founded in Frankfurt am Main (Germany) within the framework of the LOEWE Programme, a State Government of Hesse initiative for the development of scientific and economic excellence. The mission of the new centre (BiK-F) is to carry out internationally outstanding research on the interactions of organismic […]
Effects of the nanomaterial titanium dioxide NM-105 were studied in a sediment/water system with Lumbriculus variegatus according to OECD test guideline 225. Test media were prepared by mixing NM105 suspensions and the sediment-overlying water. Nominal test concentrations were confirmed by chemical analysis of Ti concentrations in the test media. Effects of titanium dioxide (NM-105) were […]
The environmental risks related to human and veterinary pharmaceuticals have to be assessed according to legal requirements within the authorisation procedures for pharmaceuticals. If a risk for the environment is indicated, risk mitigation measures should be proposed by the applicant and implemented within the risk management. The authorisation of a veterinary pharmaceutical can be refused […]
The aim of this project was to assess the relevance of joint effects related to plant protection products and biocidal products. Based on a general analysis of the concepts of mixture toxicity and their application, as well as a detailed analysis of the current environmental risk assessment schemes and their limitations, options were developed for […]
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