Development of ecotoxicological tests with biocides and eluates: verification of the suitability of the embryo test with the zebrafish (Danio rerio, DarT)

The project explored the suitability of the fish embryo toxicity test with the zebrafish, Danio rerio, (DarT) as a tool to screen for additive and non-additive effects among biocidal substances. Five biocidal products from the product type 8 (curative and preventive wood preservatives) and their individual active substances were tested in the DarT. Overall, the […]

Development of a gene expression fish embryo test as an alternative for chronic fish tests: analysis of toxic effects using differential gene expression in the Danio rerio embryo test (Gene-DarT)

Acute and chronic fish tests are performed for the registration of chemicals, pesticides, biocides and pharmaceuticals. While the fish embryo test has been developed as an alternative to the acute fish test, so far no alternatives for chronic fish tests are available. Therefore, the fish embryo test with the zebrafish (Danio rerio) was extended by […]