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New publication: Prospective environmental risk assessment of mixtures in wastewater treatment plant effluents

The aquatic environment is continually exposed to a complex mixture of chemicals, with effluents of wastewater treatment plants (WWTPs) as one key source. The aim of the present study was to investigate whether environmental risk assessments addressing individual substances are sufficiently protective for such mixtures. Based on a literature review of chemicals reported to occur […]

Potential substances of very high concern based on environmental protection criteria of the REACH regulation: Verification by substance properties and prioritisation by relevance criteria

The REACH Regulation No. 1907/2006 introduced the concept of substances of very high concern (SHVC; Art. 57) for the control of risks to human health and the environment. In this project, the focus was on environmental concerns according to Art. 57(d) to 57(f): • Persistent, bioaccumulating and toxic substances (PBT; Art. 57(d)) • Very persistent and […]

Review and enhancement of new risk assessment concepts under REACH

Within REACH, it is possible to waive standard tests that would be required for a chemical, if the available information from other tests and / or non-testing information (e.g. QSARs, grouping, read across) is considered sufficient to draw a reliable conclusion on the endpoint of concern. This concept is described as non-testing approach in the […]

Optimized strategies for risk assessment of industrial chemicals through integration of non-test and test information (OSIRIS)

OSIRIS (Optimized Strategies for Risk Assessment of Chemicals based on Intelligent Testing) develops integrated testing strategies (ITS) which can be used for the European Union regulation REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) to significantly increase the use of non-testing information for risk assessment of industrial chemicals and regulatory decision making. This includes alternative […]