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New publication: Compartment‐specific screening tools for persistence – potential role and application in the regulatory context

The persistence assessment under REACH relies on compartment‐specific degradation half‐lives derived from laboratory simulation studies with surface water, aquatic sediment or soil. Although these data are given priority, they are not available for most of the compounds. Therefore, according to the integrated assessment and testing strategy for persistence assessment, results from ready biodegradability tests are […]

Report on assessment of environmental persistence

Report published on ‘Assessment of environmental persistence’

A literature study was performed to review the applicability of established and new tests for biodegradability for assessing persistence in the frame of PBT and vPvB assessments under REACH. Screening tests for ready and inherent biodegradability, proposals for enhanced ready tests as well as newly designed compartment-specific screening tests were analysed for strengths and weaknesses, […]

Improved strategy to assess chemical persistence at the water-sediment interface

The environmental fate of a compound is determined by transformation and distribution processes, which are strongly dependent on the specific environmental conditions. Biodegradability of chemicals in different environmental compartments is one of the major determinants of their environmental fate and therefore plays a crucial role in regulatory decision-making. Simulation studies according to OECD 308 (aquatic […]

Comparison of the environmental properties of parasiticides and harmonisation of the basis for environmental assessment at the EU level

Avermectin and milbemycin parasiticides have a high toxicity to non-target organisms, are often persistent and may have a potential to bioaccumulate. The present project contributes to filling gaps in the database for a complete environmental risk assessment of these parasiticides. In addition, risk management strategies for parasiticides used in pasture animals were discussed. For ivermectin […]

Registration procedures for substances of high concern: fate, behaviour, degradation and potential accumulation of potentially persistent, bioaccumulative and toxic (PBT) substances in aquatic meoscosms

Persistent, bioaccumulative and toxic (PBT) compounds deserve specific attention when considering the hazard, which these substances might cause to the environment. These circumstances are taken into account by the European Union in the REACH regulation. For example, for persistent compounds it is difficult to predict long-term effects by established risk assessment procedures, since low degradation […]