Manure is widely used as a fertilizer and applied to agricultural land. It may contain highly active chemicals like veterinary medicinal products or biocides, which enter the environment by this pathway. This is recognized by several regulatory frameworks, however, a detailed method for examining the transformation of chemicals in manure was lacking. The present publication […]
In persistence assessment, enhanced ready biodegradability tests (eRBT) are used to close the gap between screening tests and complex simulation tests. However, only few data from such tests are available, and neither guidance on the design and interpretation of eRBTs, nor suitable validity criteria have been established so far. In a practical testing programme, five […]
A proposal was prepared for the post-authorisation monitoring of veterinary medicinal products, in particular parasiticides. Such a monitoring might especially be useful for parasiticides identified as PBT substances, i.e., substances that are toxic (T), persist in the environment (P) and bioaccumulate (B). Based on a literature search, issues are discussed that have to be considered […]
A literature study was performed to review the applicability of established and new tests for biodegradability for assessing persistence in the frame of PBT and vPvB assessments under REACH. Screening tests for ready and inherent biodegradability, proposals for enhanced ready tests as well as newly designed compartment-specific screening tests were analysed for strengths and weaknesses, […]
Avermectin and milbemycin parasiticides have a high toxicity to non-target organisms, are often persistent and may have a potential to bioaccumulate. The present project contributes to filling gaps in the database for a complete environmental risk assessment of these parasiticides. In addition, risk management strategies for parasiticides used in pasture animals were discussed. For ivermectin […]
The REACH Regulation No. 1907/2006 introduced the concept of substances of very high concern (SHVC; Art. 57) for the control of risks to human health and the environment. In this project, the focus was on environmental concerns according to Art. 57(d) to 57(f): • Persistent, bioaccumulating and toxic substances (PBT; Art. 57(d)) • Very persistent and […]
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T. Junker
Hydrotox - Labor für Ökotoxikologie und Gewässerschutz GmbH 
K. Duis