New publication: Compartment‐specific screening tools for persistence – potential role and application in the regulatory context

The persistence assessment under REACH relies on compartment‐specific degradation half‐lives derived from laboratory simulation studies with surface water, aquatic sediment or soil. Although these data are given priority, they are not available for most of the compounds. Therefore, according to the integrated assessment and testing strategy for persistence assessment, results from ready biodegradability tests are […]

Improved strategy to assess chemical persistence at the water-sediment interface

The environmental fate of a compound is determined by transformation and distribution processes, which are strongly dependent on the specific environmental conditions. Biodegradability of chemicals in different environmental compartments is one of the major determinants of their environmental fate and therefore plays a crucial role in regulatory decision-making. Simulation studies according to OECD 308 (aquatic […]

Registration procedures for substances of high concern: fate, behaviour, degradation and potential accumulation of potentially persistent, bioaccumulative and toxic (PBT) substances in aquatic meoscosms

Persistent, bioaccumulative and toxic (PBT) compounds deserve specific attention when considering the hazard, which these substances might cause to the environment. These circumstances are taken into account by the European Union in the REACH regulation. For example, for persistent compounds it is difficult to predict long-term effects by established risk assessment procedures, since low degradation […]

Optimized strategies for risk assessment of industrial chemicals through integration of non-test and test information (OSIRIS)

OSIRIS (Optimized Strategies for Risk Assessment of Chemicals based on Intelligent Testing) develops integrated testing strategies (ITS) which can be used for the European Union regulation REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) to significantly increase the use of non-testing information for risk assessment of industrial chemicals and regulatory decision making. This includes alternative […]

Novel methods for integrated risk assessment of cumulative stressors in Europe (NoMiracle)

NoMiracle (Novel Methods for Integrated Risk Assessment of CumuLative stressors in Europe) supports the development and improvement of methodologies, which describe and help to understand combined stressor effects to human health and the environment. In particular, the project studies the transfer of pollutants between different environmental compartments, including how these processes are influenced by natural […]