The fish short-term reproduction assay according to OECD test guideline 229 serves as Level 3 in vivo assay within the OECD Conceptual framework for the testing and assessment of endocrine disrupting chemicals. Laboratories aiming to conduct this assay must demonstrate their ability by performing a technical proficiency study with reference compounds. ECT has successfully completed […]
Data collected by ECT in the frame of various research projects in the last decades contributed to a publication on the global abundance and diversity of earthworms. Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large […]
The Innovative Medicines Initiative (IMI) project PREMIER aims to develop a centralised, user-friendly digital assessment system accessible for all relevant stakeholders. PREMIER will also explore options to incorporate environment considerations earlier in the drug development process to inform drug design and to reduce the need of animal testing. ECT is involved in this project as […]
The Innovative Medicines Initiative (IMI) project ‘Prioritisation and risk evaluation of medicines in the environment’ (PREMIER) aims to develop a centralised, user-friendly and transparent digital assessment system accessible for all relevant stakeholders such as regulatory agencies, pharmaceutical industry, water managers and environmental non-governmental organisations. Furthermore, PREMIER will explore the options to incorporate environment considerations earlier […]
Because of their usually high molecular weight, polymers are generally considered as being of low environmental concern and are, therefore, exempted from registration and evaluation within REACH. This exemption is currently being reviewed by the European Commission. Against this background, data on the environmental fate and effects of selected water-soluble synthetic organic polymers used in […]
Protecting the structure and functioning of soil ecosystems is one of the central aims of current regulations of chemicals. This is, for instance, shown by the emphasis on the protection of key drivers and ecosystem services proposed by EFSA in the protection goal options for soil organisms. Such targets require insight into soil biodiversity, its […]
A project funded by the German Environment Agency was performed to provide scientifically robust and practical information on the variability of the endpoints assessed in earthworm field studies, the statistical significance of the results and the level of the statistically detectable effects of the chemicals tested with the aim of developing suggestions for improving the […]
Research on potential side-effects of pesticides on beneficial organisms has focused on temperate test species and conditions. Thus, there is a need for ecotoxicity studies for pesticides under tropical conditions. The present study aimed to compare the acute and chronic toxicity of the fungicide carbendazim to the earthworm Eisenia fetida under tropical and temperate conditions. […]
ECT remains to be open and operative during the current COVID-19 pandemic. We take thorough precautions to avoid any health impact and risks for ECT employees, meaning the increase of remote work options and practicing social distancing where remote work is not possible. Access to our facilities is strongly restricted and any business travelling on […]
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