Entries by wp_admin
Hyalella azteca bioconcentration test (HYBIT)
ECHA recently announced that the Hyalella azteca bioconcentration test (HYBIT) can fulfil the standard information requirement under REACH for bioaccumulation, unless dietary exposure is required (read more). Thereby, the bioconcentration test (OECD TG 305) with fish will be replaced on a case-by-case basis with a test system that uses freshwater amphipods, i.e. non-vertebrates. A test […]
New publication on TKTD modeling of sublethal endpoints for time‐variable toxicant exposure of Ceriodaphnia
Toxicokinetic-toxicodynamic (TKTD) modeling can integrate all available data from individual‐level bioassays into a single framework and enable refined risk assessments by extrapolating from laboratory results to time‐variable exposure scenarios. Dynamic energy budget (DEB) models coupled with TKTD modules (DEB-TKTD) are an approach to assess and predict sublethal effects of chemicals on individual organisms. However, thorough […]
Fish short-term reproduction assay (OECD 229)
The fish short-term reproduction test is an in vivo screening assay that provides information about possible endocrine-mediated effects on adult fish. Within the OECD Conceptual framework for the testing and assessment of endocrine disrupting chemicals, it is a level 3 assay. We perform this test according to OECD test guideline 229 (Fish short-term reproduction assay, […]
Report published on HP 14 classification of mirror entries in the List of Wastes
Depending on its composition, waste from mirror entries has to be categorized as hazardous or non-hazardous. The hazard property ‘ecotoxic’ (HP 14) can be evaluated based on the content of hazardous substances in the respective waste or using ecotoxicity tests with samples and eluates of this waste. At the EU level, specific requirements for the […]
Fish early life stage test
Fish early-life stage tests are required for environmental risk assessments of industrial chemicals, plant protection products, biocides, and human and veterinary pharmaceuticals to evaluate chronic effects on the sensitive early life stages of fish. We perform these tests according to OECD test guideline 210 (Fish, early-life stage toxicity test, revised in 2013) in compliance with […]
Successful renewal of ECT’s GLP certificate – now also including category 1 (Physical-chemical testing)
ECT’s certificate of Good Laboratory Practice (GLP) has been successfully renewed in April 2024, for the 9th time since 1994. The successful assessment of conformity with GLP included ECT’s recently established analytical department and electronic raw data archive.
Meet ECT and the SynTech Research Group at the SETAC Europe 34th Annual Meeting
The SETAC Europe 34th annual meeting takes place in Seville (Spain) from 5 to 9 May 2024. ECT contributes to this meeting with several presentations. Please come and meet us at our presentations or at the SynTech Research Group booth 243!
R&D activities for private companies
ECT received formal approval for carrying out R&D activities for private companies, which enables a tax credit (Crédit d’Impôt Recherche, CIR) for our French customers.
In-house analytical services
In-house analytical services under GLP are now available at ECT. Analytical verification of actual test concentrations is essential in ecotoxicity studies, and we are now prepared to provide this service in-house.