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Publication on enhanced ready biodegradability screening tests

In persistence assessment, enhanced ready biodegradability tests (eRBT) are used to close the gap between screening tests and complex simulation tests. However, only few data from such tests are available, and neither guidance on the design and interpretation of eRBTs, nor suitable validity criteria have been established so far. In a practical testing programme, five […]

Further development of simple test systems for the evaluation of potential PBT substances: How to bridge the gap between screening tests and complex studies?

The first aim of the project was to assess whether the existing OECD test guidelines for ready biodegradability of chemicals (OECD test guidelines 301 A–D and 310) can be harmonized. The gained insights were discussed at an international expert workshop in April 2019. Laboratory experiments were performed for five test substances to verify the impact […]

Optimized strategies for risk assessment of industrial chemicals through integration of non-test and test information (OSIRIS)

OSIRIS (Optimized Strategies for Risk Assessment of Chemicals based on Intelligent Testing) develops integrated testing strategies (ITS) which can be used for the European Union regulation REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) to significantly increase the use of non-testing information for risk assessment of industrial chemicals and regulatory decision making. This includes alternative […]