In persistence assessment, enhanced ready biodegradability tests (eRBT) are used to close the gap between screening tests and complex simulation tests. However, only few data from such tests are available, and neither guidance on the design and interpretation of eRBTs, nor suitable validity criteria have been established so far. In a practical testing programme, five […]
The first aim of the project was to assess whether the existing OECD test guidelines for ready biodegradability of chemicals (OECD test guidelines 301 A–D and 310) can be harmonized. The gained insights were discussed at an international expert workshop in April 2019. Laboratory experiments were performed for five test substances to verify the impact […]
A literature study was performed to review the applicability of established and new tests for biodegradability for assessing persistence in the frame of PBT and vPvB assessments under REACH. Screening tests for ready and inherent biodegradability, proposals for enhanced ready tests as well as newly designed compartment-specific screening tests were analysed for strengths and weaknesses, […]
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