ecotoxicity Archive - ECT Oekotoxikologie GmbH

Tag Archive for: ecotoxicity

New publication on TKTD modeling of sublethal endpoints for time‐variable toxicant exposure of Ceriodaphnia

October 2024

Toxicokinetic-toxicodynamic (TKTD) modeling can integrate all available data from individual‐level bioassays into a single framework and enable refined risk assessments by extrapolating from laboratory results to time‐variable exposure scenarios. Dynamic energy budget (DEB) models coupled with TKTD modules (DEB-TKTD) are an approach to assess and predict sublethal effects of chemicals on individual organisms. However, thorough […]

New publication: Minimizing experimental testing on fish for legacy pharmaceuticals

February 2023

Lead by Anja Coors, a team of partners in the IMI-funded project ‘Prioritisation and risk evaluation of medicines in the environment’ (PREMIER) developed and recently published a decision tree that shall help to minimize animal testing within PREMIER and beyond. The risk-driven decision tree uses a combination of experimental testing with non-vertebrates and a fish-specific […]

Multigeneration testing in soil invertebrates

D. Leib

Critical review and proposal for multigenerational testing in standard soil invertebrates

October 2022

Standard laboratory tests to evaluate the effects of stressors (in most cases chemicals) on soil organisms offer a good compromise between feasibility and outcome, i.e. they should be reproducible and provide robust results. However, these tests may underestimate potential effects of prolonged exposures, particularly for persistent contaminants. In the last years, there was an increase […]

Test setup - enhanced ready biodegradability test

Hydrotox - Labor für Ökotoxikologie und Gewässerschutz GmbH

Publication on enhanced ready biodegradability screening tests

May 2022

In persistence assessment, enhanced ready biodegradability tests (eRBT) are used to close the gap between screening tests and complex simulation tests. However, only few data from such tests are available, and neither guidance on the design and interpretation of eRBTs, nor suitable validity criteria have been established so far. In a practical testing programme, five […]

T. Junker

Review of the environmental fate and effects of two UV filter substances

December 2021

Sunscreens containing UV filter substances, such as octocrylene (OCR) and butyl-methoxydibenzoylmethane (BMDBM), have been increasingly used to protect human skin against UV radiation. Both substances have been detected in monitoring studies in the freshwater and marine environment, and there has been concern about potential effects on aquatic organisms. In the present work, the environmental fate […]

Environemtal fate and effects of water-soluble polymers

K. Duis

Review on the environmental fate and effects of water-soluble synthetic organic polymers

March 2021

Because of their usually high molecular weight, polymers are generally considered as being of low environmental concern and are, therefore, exempted from registration and evaluation within REACH. This exemption is currently being reviewed by the European Commission. Against this background, data on the environmental fate and effects of selected water-soluble synthetic organic polymers used in […]

Intelligence-led Assessment of Pharmaceuticals in the Environment (iPiE)

May 2015

Active pharmaceutical ingredients (APIs) of medicines for human use can be released to the environment during the manufacturing process, following use by patients or when unused medicines are disposed of in an incorrect manner. As APIs are biologically active compounds, concerns have been raised about the potential effects of APIs in the environment on human […]

ECT organises a ring test with dung beetles

March 2015

European legislation requires testing of parasiticides using, among others, dung beetles (OECD GD 122). Currently, Aphodius constans, a dweller species, has been approved as a test species for residues in dung. However, results of tests using A. constans may not be relevant for tunneler species.

K. Duis

Comparison of the environmental properties of parasiticides and harmonisation of the basis for environmental assessment at the EU level

February 2015

Avermectin and milbemycin parasiticides have a high toxicity to non-target organisms, are often persistent and may have a potential to bioaccumulate. The present project contributes to filling gaps in the database for a complete environmental risk assessment of these parasiticides. In addition, risk management strategies for parasiticides used in pasture animals were discussed. For ivermectin […]

Novel processing routes for effective sewage sludge management (ROUTES)

December 2012

The ROUTES project aimed to evaluate new routes of sewage sludge treatment and management matching the needs of different wastewater origins and different digested sludge utilisations. Elimination of micropollutants was targeted for agricultural sludge application, and minimising the production volume for other sludge disposal routes. Research of ECT in sludge-soil interactions focussed on three aspects: […]