Tag Archive for: chronic fish toxicity

New publication: Minimizing experimental testing on fish for legacy pharmaceuticals

Lead by Anja Coors, a team of partners in the IMI-funded project ‘Prioritisation and risk evaluation of medicines in the environment’ (PREMIER) developed and recently published a decision tree that shall help to minimize animal testing within PREMIER and beyond. The risk-driven decision tree uses a combination of experimental testing with non-vertebrates and a fish-specific […]

Development of a gene expression fish embryo test as an alternative for chronic fish tests: analysis of toxic effects using differential gene expression in the Danio rerio embryo test (Gene-DarT)

Acute and chronic fish tests are performed for the registration of chemicals, pesticides, biocides and pharmaceuticals. While the fish embryo test has been developed as an alternative to the acute fish test, so far no alternatives for chronic fish tests are available. Therefore, the fish embryo test with the zebrafish (Danio rerio) was extended by […]