Tag Archive for: active pharmaceutical ingredient

Publication on pharmaceutical pollution of the world’s rivers

ECT contributed to a recently published global reconnaissance of pharmaceutical pollution in rivers. Reaching out to colleagues globally and engaging them in a world-wide sampling campaign, the team around John Wilkinson and Alistair Boxall from the University of York measured the concentrations of 61 pharmaceuticals in 258 rivers, representing 1,052 locations in 104 countries across […]

Publication: Evidence for specific receptor-mediated toxicity of pharmaceuticals in aquatic organisms

The toxicity of 17 active pharmaceutical ingredients (APIs) was investigated using standardized acute and chronic tests with Daphnia magna and 2 algae species. Chronic toxicity was generally greater for Daphnia than for algae. Compilation of additional data resulted in 100 APIs for which the acute-to-chronic ratio (ACR) was determined for Daphnia. The frequency of high…

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Intelligence-led Assessment of Pharmaceuticals in the Environment (iPiE)

Active pharmaceutical ingredients (APIs) of medicines for human use can be released to the environment during the manufacturing process, following use by patients or when unused medicines are disposed of in an incorrect manner. As APIs are biologically active compounds, concerns have been raised about the potential effects of APIs in the environment on human […]