Adaptation of the current earthworm field study guideline

Adaptation of the current earthworm field study guideline in order to harmonise field testing and risk evaluation for earthworms

This project has three aims: (1) to compile and critically evaluate standardised earthworm field studies in order to optimise the current test design, (2) to perform a pilot earthworm field study following the improved test design, and (3) to prepare an OECD draft guidance document. After having discussed different design options within the OECD-GSIG expert […]

Review of the ecotoxicity of boric acid in standard laboratory tests with plants and soil organisms

To verify the sensitivity of ecotoxicological tests, reference substances with known toxicity are regularly tested. Ideally, such substances lack specificity in their mode action, are bioavailable and readily attainable, and their chemical characterisation is cost-effective. Boric acid satisfies these criteria, but has – due to reproductive effects in humans – most recently been characterised as […]

New publication: Extended plant tests for the environmental risk assessment of veterinary pharmaceuticals

Residues of veterinary pharmaceuticals enter the environment via application of manure onto agricultural land, where particularly antibiotics can cause phytotoxicity. Terrestrial plant tests according to OECD test guideline 208 are part of the environmental risk assessment of veterinary pharmaceuticals. However, this standard approach might not be appropriate for veterinary medicinal products forming non-extractable residues or transformation products in manure and manure-amended soil. To assess such products, a new test design including a more realistic exposure scenario via manure application is needed.

Investigation of sublethal endpoints in dung organisms as a prerequisite for the implementation of terrestrial ecotoxicological studies within the environmental risk assessment of veterinary pharmaceuticals

The aims of this project were the compilation and publication of the results of workshops with international dung fauna experts (Aveiro group) and the further improvement of existing laboratory tests with dung beetles and dung flies. Two publications were prepared: first, recommendations for the preparation, performance and assessment of field studies with dung organisms, and […]