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Publication on validation of a method to determine transformation of chemicals in manure

Manure is widely used as a fertilizer and applied to agricultural land. It may contain highly active chemicals like veterinary medicinal products or biocides, which enter the environment by this pathway. This is recognized by several regulatory frameworks, however, a detailed method for examining the transformation of chemicals in manure was lacking. The present publication […]

Publication on enhanced ready biodegradability screening tests

In persistence assessment, enhanced ready biodegradability tests (eRBT) are used to close the gap between screening tests and complex simulation tests. However, only few data from such tests are available, and neither guidance on the design and interpretation of eRBTs, nor suitable validity criteria have been established so far. In a practical testing programme, five […]

Report on assessment of environmental persistence

Report published on ‘Assessment of environmental persistence’

A literature study was performed to review the applicability of established and new tests for biodegradability for assessing persistence in the frame of PBT and vPvB assessments under REACH. Screening tests for ready and inherent biodegradability, proposals for enhanced ready tests as well as newly designed compartment-specific screening tests were analysed for strengths and weaknesses, […]

Comparison of the environmental properties of parasiticides and harmonisation of the basis for environmental assessment at the EU level

Avermectin and milbemycin parasiticides have a high toxicity to non-target organisms, are often persistent and may have a potential to bioaccumulate. The present project contributes to filling gaps in the database for a complete environmental risk assessment of these parasiticides. In addition, risk management strategies for parasiticides used in pasture animals were discussed. For ivermectin […]

Potential substances of very high concern based on environmental protection criteria of the REACH regulation: Verification by substance properties and prioritisation by relevance criteria

The REACH Regulation No. 1907/2006 introduced the concept of substances of very high concern (SHVC; Art. 57) for the control of risks to human health and the environment. In this project, the focus was on environmental concerns according to Art. 57(d) to 57(f): • Persistent, bioaccumulating and toxic substances (PBT; Art. 57(d)) • Very persistent and […]

Registration procedures for substances of high concern: fate, behaviour, degradation and potential accumulation of potentially persistent, bioaccumulative and toxic (PBT) substances in aquatic meoscosms

Persistent, bioaccumulative and toxic (PBT) compounds deserve specific attention when considering the hazard, which these substances might cause to the environment. These circumstances are taken into account by the European Union in the REACH regulation. For example, for persistent compounds it is difficult to predict long-term effects by established risk assessment procedures, since low degradation […]